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Sulfonamides are:

a.not metabolized by the cytochrome P450 enzyme system in liver nor via conjugation and acetylation; therefore, patients who are slow acetylators have a decreased risk of toxicity.

b.not metabolized by the cytochrome P450 enzyme system in the liver but are metabolized in the liver via conjugation and acetylation; therefore, patients who are slow acetylators have an increased risk of toxicity.

c.metabolized by the cytochrome P450 enzyme system in the liver and via conjugation and acetylation; therefore, patients who are slow acetylators have an increased risk of toxicity.

d.not metabolized by the cytochrome P450 enzyme system in the liver but are metabolized in the liver via conjugation and acetylation; therefore, patients who are rapid acetylators have an increased risk of toxicity.

SCIENCE
HEALTH SCIENCE
NURSING
NURSING N512

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