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Marty Q, a 36-year-old middle school teacher, has been diagnosed with acute myelogenous leukemia (AML). After hearing his treatment options and conferring with his family, he decides to undergo aggressive high-dose chemotherapy, total body irradiation (TBI), and hematopoietic stem cell transplantation (HSCT).

The oncologist explains to Marty two HSCT options: autologous and allogeneic. How would you respond if Marty asked you to clarify the pros and cons of these two options?
Marty opts to have an allogeneic transplant. His younger sister volunteers to donate. It is decided to use the peripheral blood method rather than a bone marrow aspiration to obtain the stem cells. Marty asks you what his sister will experience. Explain what you can about this procedure.

Clinical update: Marty has gone through the preparation, or conditioning, for stem-cell engraftment.

What is the purpose of conditioning?
How will total body irradiation be performed?

Clinical update: Marty has had his hematopoietic stem-cell transplant and is now awaiting engraftment.

While Marty waits for engraftment, how will his environment be controlled?
List at least three common complications of hematopoietic stem-cell transplant that the nurse will need to monitor for posttransplant. 
 
SCIENCE
HEALTH SCIENCE
NURSING
VNSG 1171

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