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Reference: Introduction to Human Disease Pathophysiology for Health Professionals, Seventh Edition. Authors Agnes G. Loeffler and Michael N. Hart. See chapter 5: pages 63 – 89
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1) Chart: Benign vs Malignant. Compare and contrast each characteristics for benign and malignant neoplasm.
Growth Characteristics Benign Malignant
Growth Rates  Â
Borders  Â
Metastasis  Â
Mitotic Figure  Â
Differentiation  Â
Nuclear Size  Â
Nucleoli  Â
2) Table: Compare and Contrast Oncogenes and Tumor Suppressor Genes. List at least 3 traits or facts of each.
Oncogenes Tumor Suppressor
Genes
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3) Table: Causes of Altered Gene Expression. Lists some details about what each of the following factors can elicit and sources of each.
Cause of Altered
Gene Expression NOTES
Ionizing Radiation Â
Chemicals Â
Microorganisms Â
Familial Predisposition Â
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4) Table: Cancers cause the following issues. Provide two or three notes on each issue. Notes should focus on why this issue is happening (the pathological cause) and a possible treatment.
Cancer Caused
Issue NOTES
Mass Â
Pain Â
Hemorrhage Â
Pathologic Fracture Â
Infection Â
Anemia Â
Cachexia Â
Hormone Production Â
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SCIENCE
HEALTH SCIENCE
NURSING
HIM 210