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Of the following medications, which ones are considered first-line in treatment of an acute manic episode of bipolar disorder (assuming monotherapy)? I. Lithium II. Fluoxetine III. Aripiprazole IV. Risperidone V. Ziprasidone VI. Venlafaxine VII. Quetiapine III. Valproate A. Il, Ill, and VIII only B. I, III, IV. & VII, and VIII only C. II, III, and VI only D. I only E. All that are listed are appropriate in treating the acute episode.
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